RASGRF2

Across TCGA patient cohorts, RASGRF2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,018 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RASGRF2-associated genes across cancer lineages are TMEM130, IRAG1, and SYNDIG1. Each is linked with RASGRF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RASGRF2-to-partner and partner-to-RASGRF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGRF2 versus TMEM130 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRF2→partner) and Y-score (partner→RASGRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM130 →	+1.584	+0.553	<.001	<.001	3	6
BRCA	IRAG1 →	+1.013	+0.577	<.001	<.001	3	6
BRCA	SYNDIG1 →	+1.533	+0.554	<.001	<.001	3	5
BRCA	ZNF423 →	+0.576	+0.325	<.001	.001	3	5
BRCA	SGIP1 →	+0.840	+0.571	<.001	<.001	3	5
BRCA	GLT8D2 →	+1.225	+0.534	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,018 associations by consensus.

RASGRF2 vs TMEM130 — GBM

Explore this scatter interactively →