RASGRF2

Across TCGA cell cohorts, RASGRF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,953 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASGRF2-associated GO terms across cancer lineages are Protein polyubiquitination, Cellular response to type I interferon, and Nucleic acid catabolic process. Each is linked with RASGRF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both RASGRF2-to-partner and partner-to-RASGRF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by RASGRF2-low versus RASGRF2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRF2→partner) and Y-score (partner→RASGRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein polyubiquitination →	+0.022	+0.132	<.001	.001	3	8
SKIN	Cellular response to type I interferon →	+0.062	+0.591	<.001	<.001	3	7
BLOOD_Leukemia	Nucleic acid catabolic process →	+0.033	+0.152	<.001	.004	3	7
BLOOD_Leukemia	Regulation of mRNA splicing, via spliceosome →	+0.047	+0.099	.002	<.001	3	7
SKIN	Response to type I interferon →	+0.059	+0.534	<.001	.001	3	7
SKIN	Intracellular transport of virus →	+0.131	+0.877	.002	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,953 associations by consensus.

Protein polyubiquitination by RASGRF2 expression — BLOOD_Leukemia

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