RASGRF1

Across TCGA patient cohorts, RASGRF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,699 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RASGRF1-associated genes across cancer lineages are PRODH, MFNG, and PIK3IP1. Each is linked with RASGRF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASGRF1-to-partner and partner-to-RASGRF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGRF1 versus PRODH in GBM, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRF1→partner) and Y-score (partner→RASGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.836	+0.374	.006	.006	3	1
GBM	MFNG →	+0.557	+0.377	.004	.005	3	1
GBM	PIK3IP1 →	+0.557	+0.299	<.001	<.001	3	1
GBM	SOX10 →	+1.758	+0.396	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.160	+0.382	.001	.003	3	1
GBM	TPTEP1 →	+0.751	+0.368	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,699 associations by consensus.

RASGRF1 vs PRODH — GBM

Explore this scatter interactively →