RASGRF1

Across TCGA patient cohorts, RASGRF1 mutation is significantly associated with the RNA expression of many other genes, with 5,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASGRF1-associated genes across cancer lineages are CD207, MED9, and BUB3. Each is linked with RASGRF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RASGRF1-to-partner and partner-to-RASGRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD207 grouped by RASGRF1-low versus RASGRF1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRF1→partner) and Y-score (partner→RASGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD207 →	-0.366	-1.793	.005	.004	3	4
UCEC	MED9 →	+0.315	+2.131	<.001	<.001	3	4
UCEC	BUB3 →	+0.480	+2.812	<.001	<.001	3	4
UCEC	RAD51 →	+0.766	+2.110	<.001	<.001	3	4
UCEC	TIPIN →	+0.631	+2.390	<.001	<.001	3	4
UCEC	EMID1 →	-1.274	-3.237	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,430 associations by consensus.

CD207 by RASGRF1 expression — COAD

Explore this box plot interactively →