RASGRF1

Across TCGA cell cohorts, RASGRF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,804 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RASGRF1-associated GO terms across cancer lineages are Regulation of proteolysis, Blood coagulation, fibrin clot formation, and Positive regulation of extrinsic apoptotic signaling pathway. Each is linked with RASGRF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RASGRF1-to-partner and partner-to-RASGRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteolysis grouped by RASGRF1-low versus RASGRF1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRF1→partner) and Y-score (partner→RASGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of proteolysis →	+0.085	+0.822	<.001	.009	2	10
LUNG_NSCLC_LUSC	Blood coagulation, fibrin clot formation →	+0.393	+1.528	.002	.002	3	9
LUNG_NSCLC_LUAD	Positive regulation of extrinsic apoptotic signaling pathway →	+0.081	+0.808	.001	.003	3	9
LUNG_NSCLC_LUSC	Protein activation cascade →	+0.465	+1.891	<.001	<.001	3	8
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.055	+1.193	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway →	+0.159	+1.319	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,804 associations by consensus.

Regulation of proteolysis by RASGRF1 expression — OVARY

Explore this box plot interactively →