RASAL1

Across TCGA cell cohorts, RASAL1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASAL1-associated genes across cancer lineages are VN1R4, FSHB, and SCGB1C2. Each is linked with RASAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASAL1-to-partner and partner-to-RASAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R4 grouped by RASAL1-low versus RASAL1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASAL1→partner) and Y-score (partner→RASAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	VN1R4 →	+0.098	+5.754	<.001	.002	3	1
LUNG_SCLC	FSHB →	+0.012	+5.029	<.001	.006	3	1
LUNG_SCLC	SCGB1C2 →	+0.341	+5.029	<.001	.006	3	1
BLOOD_Leukemia	OR1L6 →	+0.023	+4.060	<.001	.003	3	1
BLOOD_Leukemia	OR52M1 →	+0.013	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

VN1R4 by RASAL1 expression — CNS

Explore this box plot interactively →