RASA4

Across TCGA patient cohorts, RASA4 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RASA4-associated genes across cancer lineages are MIR379, MIR134, and RNU6-380P. Each is linked with RASA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASA4-to-partner and partner-to-RASA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR379 grouped by RASA4-low versus RASA4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA4→partner) and Y-score (partner→RASA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR379 →	+0.388	+7.816	<.001	.008	3	1
SKCM	MIR134 →	+0.527	+7.816	<.001	.008	3	1
SKCM	RNU6-380P →	+0.398	+7.816	<.001	.008	3	1
SKCM	LINC01755 →	+0.114	+7.816	<.001	.008	3	1
UCEC	MIR3683 →	+0.777	+7.245	<.001	<.001	3	1
UCEC	WBP1LP6 →	+0.212	+7.245	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MIR379 by RASA4 expression — SKCM

Explore this box plot interactively →