RASA4

Across TCGA cell cohorts, RASA4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RASA4-associated genes across cancer lineages are OR10W1, OR6C4, and GAGE12D. Each is linked with RASA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASA4-to-partner and partner-to-RASA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by RASA4-low versus RASA4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA4→partner) and Y-score (partner→RASA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LUNG_SCLC	OR6C4 →	+0.016	+5.029	<.001	.006	3	1
LUNG_SCLC	GAGE12D →	+0.590	+5.643	<.001	.002	3	1
LUNG_SCLC	GAGE12C →	+0.590	+5.643	<.001	.002	3	1
STOMACH	CCDC182 →	+0.025	+4.285	<.001	.007	3	1
STOMACH	MMP26 →	+0.505	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR10W1 by RASA4 expression — LARGE_INTESTINE

Explore this box plot interactively →