RASA3-IT1

Across TCGA pan-cancer cohorts, RASA3-IT1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RASA3-IT1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RASA3-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RASA3-IT1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and READ show a favorable association.

LIHC, KIRC, and UCEC are the cancer types where RASA3-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.539	0.808	<.001	90	view →
KIRC	OS	Tertile	All	0.746	0.835	.002	83	view →
UCEC	OS	Tertile	II,III,IV	0.891	0.735	.023	30	view →
READ	DFS	Tertile	III,IV	1.000	0.217	.013	27	view →
UVM	DFS	Tertile	III,IV	0.347	0.656	.014	26	view →
MESO	OS	Tertile	All	0.216	0.617	.003	15	view →
STAD	DFS	Quartile	III,IV	0.434	0.596	.025	12	view →
SKCM	OS	Quartile	All	0.711	0.809	.012	9	view →
COAD	OS	Tertile	IV	0.870	0.330	.037	9	view →
PCPG	DFS	Quartile	All	0.976	0.790	.010	7	view →
LUSC	OS	Tertile	III,IV	0.763	0.518	.045	6	view →
SARC	OS	Median	All	0.436	0.573	.009	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RASA3-IT1–LIHC (OS)

Open the LIHC breakdown →