RARRES1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RARRES1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RARRES1-associated genes across cancer lineages are H2BW2, MAS1, and ST8SIA3. Each is linked with RARRES1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RARRES1-to-partner and partner-to-RARRES1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BW2 grouped by RARRES1-low versus RARRES1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RARRES1→partner) and Y-score (partner→RARRES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTH2BW2 →+0.038+4.672.003.00231
BREASTMAS1 →+0.005+4.781<.001.00331
BREASTST8SIA3 →+0.053+4.199<.001.00731
BREASTEFCAB3 →+0.020+4.357<.001.00411
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

H2BW2 by RARRES1 expression — BREAST

Box plot of H2BW2 in RARRES1-low vs RARRES1-high samples in BREAST.

Explore this box plot interactively →

Exploration