RARB

Across TCGA patient cohorts, RARB mutation is significantly associated with the RNA expression of many other genes, with 4,156 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RARB-associated genes across cancer lineages are RPL26, VDAC2, and MYL12B. Each is linked with RARB in more than 2 cancer types. Because this analysis shows association rather than direction, both RARB-to-partner and partner-to-RARB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL26 grouped by RARB-low versus RARB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RARB→partner) and Y-score (partner→RARB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL26 →	+0.481	+2.103	.004	.003	3	3
UCEC	VDAC2 →	+0.424	+3.917	.003	<.001	3	3
UCEC	MYL12B →	+0.297	+2.080	.003	<.001	3	3
UCEC	RN7SL134P →	+0.088	+1.821	.002	.005	3	2
BLCA	RNU6-429P →	+0.381	+4.051	<.001	.001	3	2
CESC	GM2AP1 →	+0.107	+3.760	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,156 associations by consensus.

RPL26 by RARB expression — UCEC

Explore this box plot interactively →