RARA

Across TCGA patient cohorts, RARA RNA expression is significantly associated with the protein abundance of many other proteins, with 13,310 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RARA-associated proteins across cancer lineages are RPL12, RPL5, and SNX9. Each is linked with RARA in more than 4 cancer types. Because this analysis shows association rather than direction, both RARA-to-partner and partner-to-RARA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RARA versus RPL12 in OV, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RARA→partner) and Y-score (partner→RARA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPL12 →	-0.285	-1.264	<.001	<.001	3	5
OV	RPL5 →	-0.228	-1.175	<.001	<.001	3	4
BRCA	SNX9 →	+0.285	+0.915	<.001	.003	3	4
BRCA	TKFC →	+0.407	+1.169	<.001	<.001	3	4
LSCC	NID1 →	+0.451	+0.520	<.001	<.001	3	4
BRCA	AGO1 →	+0.323	+1.125	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,310 associations by consensus.

RARA vs RPL12 — OV

Explore this scatter interactively →