RAPSN

Across TCGA cell cohorts, RAPSN mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible RAPSN-associated genes across cancer lineages are SEC14L3, LECT2, and HMHB1. Each is linked with RAPSN in more than 1 cancer types. Because this analysis shows association rather than direction, both RAPSN-to-partner and partner-to-RAPSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEC14L3 grouped by RAPSN-low versus RAPSN-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAPSN→partner) and Y-score (partner→RAPSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SEC14L3 →	+0.011	+4.217	<.001	.005	3	1
URINARY_TRACT	LECT2 →	+0.848	+4.217	<.001	.005	3	1
URINARY_TRACT	HMHB1 →	+0.072	+4.087	<.001	.009	3	1
URINARY_TRACT	MS4A6E →	+0.032	+4.087	<.001	.009	3	1
URINARY_TRACT	OR1A1 →	+0.005	+4.087	<.001	.009	3	1
URINARY_TRACT	TEX44 →	+0.025	+5.044	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

SEC14L3 by RAPSN expression — URINARY_TRACT

Explore this box plot interactively →