RAPGEFL1

Across TCGA patient cohorts, RAPGEFL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,418 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAPGEFL1-associated proteins across cancer lineages are EPB41L1, PDIA4, and RRBP1. Each is linked with RAPGEFL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RAPGEFL1-to-partner and partner-to-RAPGEFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAPGEFL1 versus EPB41L1 in HNSC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAPGEFL1→partner) and Y-score (partner→RAPGEFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EPB41L1 →	+0.590	+1.184	<.001	<.001	3	6
GBM	PDIA4 →	-0.426	-0.487	<.001	<.001	3	5
GBM	RRBP1 →	-0.389	-0.610	<.001	<.001	3	5
LSCC	CORO2A →	+0.557	+1.339	<.001	<.001	3	5
GBM	FHOD1 →	-0.439	-0.587	<.001	<.001	3	5
LUAD	HSP90B1 →	-0.383	-0.652	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,418 associations by consensus.

RAPGEFL1 vs EPB41L1 — HNSC

Explore this scatter interactively →