RAP2B

Across TCGA pan-cancer cohorts, RAP2B Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RAP2B data layer compared with 25 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RAP2B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAP2B expression acts as an unfavorable survival marker.

LIHC, CESC, and UCEC are the cancer types where RAP2B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	III,IV	0.076	0.360	.001	24	view →
CESC	OS	Median	III,IV	0.068	0.756	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	All	0.488	0.787	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RAP2B–LIHC (DFS)

Open the LIHC breakdown →