RAP2B

Across TCGA cell cohorts, RAP2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,492 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RAP2B-associated GO terms across cancer lineages are Negative regulation of protein polymerization, Negative regulation of calcineurin-mediated signaling, and Cell-substrate junction organization. Each is linked with RAP2B in more than 9 cancer types. Because this analysis shows association rather than direction, both RAP2B-to-partner and partner-to-RAP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein polymerization grouped by RAP2B-low versus RAP2B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP2B→partner) and Y-score (partner→RAP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of protein polymerization →	+0.111	+0.647	<.001	.002	3	10
BREAST	Negative regulation of calcineurin-mediated signaling →	+0.229	+1.033	<.001	<.001	3	9
BREAST	Cell-substrate junction organization →	+0.161	+0.812	<.001	<.001	3	9
BONE	Regulation of intracellular transport →	+0.063	+0.756	.006	.007	3	9
LARGE_INTESTINE	Regulation of fibroblast proliferation →	+0.080	+0.745	<.001	.002	3	9
BREAST	Negative regulation of calcineurin-NFAT signaling cascade →	+0.229	+1.033	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,492 associations by consensus.

Negative regulation of protein polymerization by RAP2B expression — URINARY_TRACT

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