RAP1GDS1

Across TCGA pan-cancer cohorts, RAP1GDS1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAP1GDS1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RAP1GDS1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RAP1GDS1 expression acts as an unfavorable survival marker.

LSCC, COAD, and GBM are the cancer types where RAP1GDS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.565	0.917	.001	37	view →
COAD	DFS	Median	IV	0.565	1.000	.028	12	view →
GBM	DFS	Tertile	All	0.287	0.538	.021	10	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	10	view →
CCRCC	OS	Quartile	III,IV	0.700	0.991	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAP1GDS1–LSCC (OS)

Open the LSCC breakdown →