RAP1GAP

Across TCGA patient cohorts, RAP1GAP RNA expression is significantly associated with the protein abundance of many other proteins, with 22,167 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAP1GAP-associated proteins across cancer lineages are RAP1GAP_S484, RAP1GAP_S441, and RAP1GAP_S499. Each is linked with RAP1GAP in more than 8 cancer types. Because this analysis shows association rather than direction, both RAP1GAP-to-partner and partner-to-RAP1GAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAP1GAP versus RAP1GAP_S484 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1GAP→partner) and Y-score (partner→RAP1GAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RAP1GAP_S484 →	+1.587	+1.161	<.001	<.001	3	9
LUAD	RAP1GAP_S441 →	+1.456	+1.505	<.001	<.001	3	7
LUAD	RAP1GAP_S499 →	+1.734	+1.521	<.001	<.001	3	7
LUAD	RAP1GAP_S515 →	+1.250	+1.770	<.001	<.001	3	7
LUAD	PPP1R18 →	-0.366	-1.352	<.001	<.001	3	6
GBM	ACSS1 →	+0.610	+1.254	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,167 associations by consensus.

RAP1GAP vs RAP1GAP_S484 — LSCC

Explore this scatter interactively →