RAP1GAP

Across TCGA cell cohorts, RAP1GAP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,638 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAP1GAP-associated GO terms across cancer lineages are Aerobic respiration, Cellular response to fatty acid, and Pattern specification involved in metanephros development. Each is linked with RAP1GAP in more than 12 cancer types. Because this analysis shows association rather than direction, both RAP1GAP-to-partner and partner-to-RAP1GAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by RAP1GAP-low versus RAP1GAP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1GAP→partner) and Y-score (partner→RAP1GAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Aerobic respiration →	+0.101	+2.206	<.001	<.001	3	13
LIVER	Cellular response to fatty acid →	+0.215	+2.641	.004	.002	2	11
BONE	Pattern specification involved in metanephros development →	-1.355	-3.033	<.001	<.001	3	10
LUNG_SCLC	Cellular respiration →	+0.092	+2.365	<.001	<.001	3	10
STOMACH	Copper ion export →	-0.164	-2.277	.003	<.001	3	10
LIVER	Regulation of collagen metabolic process →	-0.152	-2.698	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,638 associations by consensus.

Aerobic respiration by RAP1GAP expression — LUNG_SCLC

Explore this box plot interactively →