RANBP9

Across TCGA patient cohorts, RANBP9 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RANBP9-associated genes across cancer lineages are TFRC, ASNS, and 14-3-3_beta. Each is linked with RANBP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP9-to-partner and partner-to-RANBP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by RANBP9-low versus RANBP9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP9→partner) and Y-score (partner→RANBP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.515	+2.584	.008	.010	3	2
UCEC	ASNS →	+0.375	+2.700	.004	.006	3	2
UCEC	14-3-3_beta →	-0.080	-2.295	.029	.033	3	1
UCEC	eEF2 →	+0.389	+2.700	.003	.005	3	1
UCEC	eIF4E →	+0.263	+2.736	<.001	<.001	3	1
UCEC	Fibronectin →	-0.325	-2.990	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

TFRC by RANBP9 expression — UCEC

Explore this box plot interactively →