RANBP9

Across TCGA pan-cancer cohorts, RANBP9 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RANBP9’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RANBP9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RANBP9 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

LIHC, LUAD, and BRCA are the cancer types where RANBP9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RANBP9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.700	<.001	9	view →
LUAD	All	III,IV	+0.612	<.001	9	view →
BRCA	All	III,IV	+0.553	<.001	6	view →
CHOL	Male	All	+1.398	<.001	5	view →
KICH	All	All	−0.605	<.001	5	view →
LUSC	All	All	+0.282	<.001	4	view →
COAD	Male	All	+0.251	.004	3	view →
READ	All	III,IV	+0.395	.011	2	view →
BLCA	Male	All	+0.365	.030	2	view →
KIRP	Male	All	−0.349	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RANBP9–LIHC

Open the LIHC breakdown →