RANBP9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RANBP9 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RANBP9-associated genes across cancer lineages are TEX43, LECT2, and HTR3B. Each is linked with RANBP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP9-to-partner and partner-to-RANBP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX43 grouped by RANBP9-low versus RANBP9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP9→partner) and Y-score (partner→RANBP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTEX43 →+0.055+4.058<.001.00932
BLOOD_LymphomaLECT2 →+0.713+4.058<.001.00931
BLOOD_LymphomaHTR3B →+0.369+3.843<.001.00731
BLOOD_LymphomaTEX50 →+0.027+4.058<.001.00931
BLOOD_LeukemiaSLC32A1 →+0.520+3.901.002.00631
BLOOD_LeukemiaVRTN →+0.043+4.339<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TEX43 by RANBP9 expression — BLOOD_Lymphoma

Box plot of TEX43 in RANBP9-low vs RANBP9-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration