RANBP6

Across TCGA patient cohorts, RANBP6 mutation is significantly associated with the RNA expression of many other genes, with 3,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RANBP6-associated genes across cancer lineages are MTA2, CENPU, and MAD2L1. Each is linked with RANBP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both RANBP6-to-partner and partner-to-RANBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTA2 grouped by RANBP6-low versus RANBP6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP6→partner) and Y-score (partner→RANBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTA2 →	+0.446	+2.108	<.001	<.001	3	3
UCEC	CENPU →	+0.673	+2.076	<.001	<.001	3	3
UCEC	MAD2L1 →	+0.612	+1.468	<.001	.001	3	3
UCEC	METTL17 →	+0.251	+3.010	.007	<.001	3	3
UCEC	CHAF1A →	+0.807	+3.684	<.001	<.001	3	3
UCEC	MAP2K1 →	+0.470	+1.653	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,914 associations by consensus.

MTA2 by RANBP6 expression — UCEC

Explore this box plot interactively →