RANBP6

Across TCGA cell cohorts, RANBP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RANBP6-associated GO terms across cancer lineages are Regulation of maintenance of sister chromatid cohesion, Regulation of maintenance of mitotic sister chromatid cohesion, and Negative regulation of gene expression via chromosomal CpG island methylation. Each is linked with RANBP6 in more than 13 cancer types. Because this analysis shows association rather than direction, both RANBP6-to-partner and partner-to-RANBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of maintenance of sister chromatid cohesion grouped by RANBP6-low versus RANBP6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP6→partner) and Y-score (partner→RANBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of maintenance of sister chromatid cohesion →	+0.102	+0.537	<.001	.002	3	14
SOFT_TISSUE	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.102	+0.537	<.001	.002	3	14
LUNG_NSCLC_LUSC	Negative regulation of gene expression via chromosomal CpG island methylation →	+0.172	+1.504	<.001	<.001	3	14
STOMACH	Protein sumoylation →	+0.087	+1.047	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.080	+0.918	<.001	.005	3	12
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.083	+1.142	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Regulation of maintenance of sister chromatid cohesion by RANBP6 expression — SOFT_TISSUE

Explore this box plot interactively →