RANBP6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RANBP6 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RANBP6-associated genes across cancer lineages are SLC6A18, REG1B, and LRRTM3. Each is linked with RANBP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP6-to-partner and partner-to-RANBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC6A18 grouped by RANBP6-low versus RANBP6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP6→partner) and Y-score (partner→RANBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaSLC6A18 →+0.024+3.514.005.00132
BLOOD_LymphomaREG1B →+0.129+3.169.002.00832
BLOOD_LymphomaLRRTM3 →+0.863+2.989<.001.00732
BLOOD_LymphomaGDF5-AS1 →+0.020+3.781<.001<.00132
PANCREASKRTAP4-5 →+0.023+5.614<.001.00231
PANCREASKRTAP1-3 →+0.042+5.000<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

SLC6A18 by RANBP6 expression — BLOOD_Lymphoma

Box plot of SLC6A18 in RANBP6-low vs RANBP6-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration