RANBP2

Across TCGA patient cohorts, RANBP2 mutation is significantly associated with the RNA expression of many other genes, with 7,665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RANBP2-associated genes across cancer lineages are RANBP1, RCC1, and UQCRC1. Each is linked with RANBP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RANBP2-to-partner and partner-to-RANBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RANBP1 grouped by RANBP2-low versus RANBP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP2→partner) and Y-score (partner→RANBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RANBP1 →	+0.639	+3.722	.001	<.001	3	6
UCEC	RCC1 →	+0.398	+1.273	<.001	<.001	3	6
UCEC	UQCRC1 →	+0.304	+1.764	<.001	<.001	3	6
UCEC	UQCRH →	+0.681	+1.495	<.001	<.001	3	6
UCEC	POC1A →	+0.414	+2.099	<.001	<.001	3	6
STAD	NDUFA8 →	+0.407	+3.207	.002	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,665 associations by consensus.

RANBP1 by RANBP2 expression — BLCA

Explore this box plot interactively →