Across TCGA patient cohorts, RANBP17 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RANBP17-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-B1, and p62 Lck ligand. Each is linked with RANBP17 in more than 3 cancer types. Because this analysis shows association rather than direction, both RANBP17-to-partner and partner-to-RANBP17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP17→partner) and Y-score (partner→RANBP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.439	+1.300	.020	.034	3	4
UCEC	Cyclin-B1 →	+0.796	+2.058	<.001	<.001	2	4
UCEC	p62 Lck ligand →	+0.297	+2.594	.004	<.001	3	3
UCEC	ASNS →	+0.408	+1.662	<.001	.010	3	3
UCEC	ATM →	-0.535	-2.794	<.001	.002	3	3
SKCM	Heregulin →	+0.136	+2.012	.048	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Exploration

RANBP17 survival (RNA) · tumor vs normal (RNA) · all RANBP17 data types