RAMP3

Across TCGA patient cohorts, RAMP3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,479 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RAMP3-associated genes across cancer lineages are PIEZO2, NEK2, and SELP. Each is linked with RAMP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAMP3-to-partner and partner-to-RAMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAMP3 versus PIEZO2 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAMP3→partner) and Y-score (partner→RAMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIEZO2 →	+2.060	+1.115	<.001	.002	3	4
LUAD	NEK2 →	-0.959	-0.439	<.001	.003	3	4
LSCC	SELP →	+1.284	+0.737	<.001	<.001	3	4
CCRCC	NANOGP11 →	+0.823	+0.900	<.001	<.001	3	4
BRCA	AGTR1 →	+4.091	+1.338	.004	.005	3	3
CCRCC	CCM2L →	+1.156	+0.717	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,479 associations by consensus.

RAMP3 vs PIEZO2 — BRCA

Explore this scatter interactively →