RAMAC

Across TCGA cell cohorts, RAMAC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,550 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RAMAC-associated GO terms across cancer lineages are RNA capping, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, and Metanephric proximal tubule development. Each is linked with RAMAC in more than 11 cancer types. Because this analysis shows association rather than direction, both RAMAC-to-partner and partner-to-RAMAC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA capping grouped by RAMAC-low versus RAMAC-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAMAC→partner) and Y-score (partner→RAMAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RNA capping →	+0.077	+0.538	<.001	<.001	3	12
STOMACH	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.126	+0.896	.002	.002	3	11
LARGE_INTESTINE	Metanephric proximal tubule development →	-0.207	-0.515	<.001	.001	3	10
OESOPHAGUS	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.090	+0.606	.003	<.001	3	9
OESOPHAGUS	RNA import into nucleus →	+0.152	+0.720	.001	.002	3	8
BLOOD_Lymphoma	Vesicle coating →	+0.094	+0.883	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,550 associations by consensus.

RNA capping by RAMAC expression — BLOOD_Leukemia

Explore this box plot interactively →