RALY

Across TCGA patient cohorts, RALY mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALY-associated genes across cancer lineages are ABHD17AP8, RNU6-543P, and MIR3154. Each is linked with RALY in more than 1 cancer types. Because this analysis shows association rather than direction, both RALY-to-partner and partner-to-RALY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD17AP8 grouped by RALY-low versus RALY-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALY→partner) and Y-score (partner→RALY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ABHD17AP8 →	+0.081	+6.064	.002	.002	3	2
SKCM	RNU6-543P →	+0.268	+7.816	<.001	.008	3	2
LUSC	MIR3154 →	+0.316	+5.191	<.001	.003	3	2
STAD	RNU6-1124P →	+0.136	+4.485	.001	.007	3	2
STAD	RBMY2AP →	+0.019	+5.506	<.001	.001	3	2
BRCA	MIR6885 →	+0.536	+5.070	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

ABHD17AP8 by RALY expression — BRCA

Explore this box plot interactively →