RALY

Across TCGA patient cohorts, RALY mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALY-associated genes across cancer lineages are Eosinophils, HSC, and Macrophages M2. Each is linked with RALY in more than 1 cancer types. Because this analysis shows association rather than direction, both RALY-to-partner and partner-to-RALY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by RALY-low versus RALY-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALY→partner) and Y-score (partner→RALY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.060	+3.173	<.001	.049	3	1
UCEC	HSC →	+0.137	+3.180	.022	.010	2	2
UCEC	Macrophages M2 →	+0.014	+3.287	.012	.008	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Eosinophils by RALY expression — LUSC

Explore this box plot interactively →