RALY

Across TCGA cell cohorts, RALY RNA expression is significantly associated with the go_rna of many other GO terms, with 3,941 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RALY-associated GO terms across cancer lineages are Regulation of centriole-centriole cohesion, Mitotic centrosome separation, and Centrosome separation. Each is linked with RALY in more than 11 cancer types. Because this analysis shows association rather than direction, both RALY-to-partner and partner-to-RALY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole-centriole cohesion grouped by RALY-low versus RALY-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RALY→partner) and Y-score (partner→RALY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of centriole-centriole cohesion →	+0.135	+0.795	<.001	<.001	3	12
CNS	Mitotic centrosome separation →	+0.151	+0.761	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Centrosome separation →	+0.119	+0.818	.002	.001	2	11
STOMACH	Regulation by virus of viral protein levels in host cell →	+0.142	+0.612	.002	.002	3	10
LUNG_SCLC	Negative regulation of ubiquitin protein ligase activity →	+0.226	+0.709	<.001	<.001	3	9
SOFT_TISSUE	Regulation of chromosome separation →	+0.091	+0.586	.006	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,941 associations by consensus.

Regulation of centriole-centriole cohesion by RALY expression — BLOOD_Lymphoma

Explore this box plot interactively →