RALGDS

Across TCGA cell cohorts, RALGDS mutation is significantly associated with the RNA expression of many other genes, with 318 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RALGDS-associated genes across cancer lineages are PSMD9, ATG4D, and KRT6C. Each is linked with RALGDS in more than 1 cancer types. Because this analysis shows association rather than direction, both RALGDS-to-partner and partner-to-RALGDS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by RALGDS-low versus RALGDS-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGDS→partner) and Y-score (partner→RALGDS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PSMD9 →	+0.627	+3.489	<.001	.001	3	2
BLOOD_Leukemia	ATG4D →	+0.582	+3.215	.006	.005	3	2
BLOOD_Leukemia	KRT6C →	+0.010	+2.522	<.001	.001	3	2
LARGE_INTESTINE	MUC5B →	+1.360	+3.064	.006	.009	3	2
LARGE_INTESTINE	FBXO16 →	+0.869	+3.502	<.001	.001	3	2
PANCREAS	TECTB →	+0.942	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

PSMD9 by RALGDS expression — BLOOD_Leukemia

Explore this box plot interactively →