RALGDS

Across TCGA pan-cancer cohorts, RALGDS RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RALGDS data layer compared with 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RALGDS RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RALGDS expression acts as an unfavorable survival marker, although some lineages such as CESC and PAAD show a favorable association.

COAD, CESC, and KIRP are the cancer types where RALGDS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Quartile	All	0.428	0.643	<.001	47	view →
CESC	DFS	Quartile	All	0.631	0.393	<.001	36	view →
KIRP	OS	Tertile	All	0.898	0.976	.011	36	view →
THCA	DFS	Tertile	III,IV	0.542	0.857	.004	24	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.017	19	view →
PAAD	OS	Quartile	All	0.601	0.167	.001	18	view →
CHOL	OS	Median	II,III,IV	0.873	0.361	.015	18	view →
SKCM	DFS	Median	II,III,IV	0.307	0.206	.018	15	view →
LIHC	DFS	Quartile	All	0.420	0.564	.016	14	view →
SCLC	DFS	Quartile	II,III,IV	0.829	0.468	.011	13	view →
STAD	DFS	Median	IV	0.196	0.620	.041	12	view →
LUAD	OS	Median	All	0.742	0.611	.029	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RALGDS–COAD (OS)

Open the COAD breakdown →