RALGAPB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RALGAPB protein abundance is significantly associated with the RNA expression of many other genes, with 14,694 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RALGAPB-associated genes across cancer lineages are RALGAPA2, LILRB2, and STX11. Each is linked with RALGAPB in more than 6 cancer types. Because this analysis shows association rather than direction, both RALGAPB-to-partner and partner-to-RALGAPB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RALGAPB versus RALGAPA2 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPB→partner) and Y-score (partner→RALGAPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARALGAPA2 →+0.909+0.252<.001<.00137
BRCALILRB2 →-0.826-0.303<.001<.00136
COADSTX11 →-0.578-0.254<.001<.00136
COADFCGR2A →-0.813-0.189<.001<.00136
GBMMLKL →-0.858-0.233<.001.00136
GBMUPP1 →-1.193-0.254<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,694 associations by consensus.

RALGAPB vs RALGAPA2 — BRCA

Per-sample scatter of RALGAPB vs RALGAPA2 in BRCA (Pearson r = 0.49).

Explore this scatter interactively →

Exploration