RALGAPB

Across TCGA patient cohorts, RALGAPB mutation is significantly associated with the RNA expression of many other genes, with 3,646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALGAPB-associated genes across cancer lineages are TRGJP2, MRPS15P1, and SPACA5. Each is linked with RALGAPB in more than 2 cancer types. Because this analysis shows association rather than direction, both RALGAPB-to-partner and partner-to-RALGAPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRGJP2 grouped by RALGAPB-low versus RALGAPB-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPB→partner) and Y-score (partner→RALGAPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TRGJP2 →	+1.220	+4.332	<.001	.002	3	3
READ	MRPS15P1 →	+0.082	+3.827	.001	.006	3	3
BLCA	SPACA5 →	+0.092	+2.138	<.001	.008	3	3
UCEC	HK2 →	+0.450	+1.447	.002	.005	3	3
COAD	SFXN1 →	+0.659	+3.740	<.001	<.001	3	3
COAD	LONRF3 →	+0.686	+3.472	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

TRGJP2 by RALGAPB expression — READ

Explore this box plot interactively →