RALA

Across TCGA patient cohorts, RALA mutation is significantly associated with the RNA expression of many other genes, with 3,347 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALA-associated genes across cancer lineages are MIR4445, FABP5P10, and COX6CP11. Each is linked with RALA in more than 1 cancer types. Because this analysis shows association rather than direction, both RALA-to-partner and partner-to-RALA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4445 grouped by RALA-low versus RALA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALA→partner) and Y-score (partner→RALA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4445 →	+0.118	+3.834	<.001	.007	3	2
UCEC	FABP5P10 →	+0.123	+1.608	.002	.004	3	2
UCEC	COX6CP11 →	+0.120	+2.283	<.001	.004	3	2
COAD	IGLVI-38 →	+0.242	+5.126	.004	.001	3	2
UCEC	BTG3-AS1 →	+0.430	+2.254	<.001	.005	3	1
UCEC	CCDC163 →	+0.472	+1.850	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,347 associations by consensus.

MIR4445 by RALA expression — UCEC

Explore this box plot interactively →