RALA

Across TCGA pan-cancer cohorts, RALA RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RALA’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RALA RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RALA is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, LIHC, and KIRP are the cancer types where RALA tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RALA RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.539	<.001	11	view →
LIHC	Female	II,III,IV	+1.131	<.001	9	view →
KIRP	All	All	+0.453	<.001	9	view →
BLCA	Male	All	+0.944	<.001	8	view →
KICH	Male	All	+1.132	<.001	7	view →
HNSC	All	All	+0.349	.011	7	view →
STAD	All	All	+0.599	.001	6	view →
COAD	Male	II,III,IV	+0.455	<.001	6	view →
UCEC	All	II,III,IV	+0.454	.003	6	view →
BRCA	All	III,IV	+0.417	<.001	6	view →
CHOL	Male	All	+2.251	<.001	5	view →
ESCA	All	All	+0.876	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RALA–KIRC

Open the KIRC breakdown →