RAG2

Across TCGA patient cohorts, RAG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,244 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAG2-associated proteins across cancer lineages are VEZF1, UPP1, and ZNF768. Each is linked with RAG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAG2-to-partner and partner-to-RAG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAG2 versus VEZF1 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAG2→partner) and Y-score (partner→RAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEZF1 →	+0.453	+0.182	<.001	<.001	3	4
HNSC	UPP1 →	-0.861	-0.153	<.001	.003	3	3
LSCC	ZNF768 →	+0.381	+0.088	.002	.003	3	3
HNSC	ZNF768_S125 →	+0.439	+0.154	<.001	.002	3	3
HNSC	ZMYM3 →	+0.367	+0.187	<.001	<.001	2	4
LSCC	ZNF513_S85 →	+0.665	+0.107	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,244 associations by consensus.

RAG2 vs VEZF1 — GBM

Explore this scatter interactively →