RAET1L

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAET1L mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAET1L-associated genes across cancer lineages are GAPDH, GATA6, and Ku80. Each is linked with RAET1L in more than 1 cancer types. Because this analysis shows association rather than direction, both RAET1L-to-partner and partner-to-RAET1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by RAET1L-low versus RAET1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAET1L→partner) and Y-score (partner→RAET1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGAPDH →+0.512+3.000.048.03631
UCECGATA6 →-0.163-2.314.036.03531
UCECKu80 →+0.327+2.472.004.01131
UCECP-Cadherin →-0.177-2.999.011.03531
UCECShc_pY317 →-0.209-2.459.004.02031
UCECSTAT3_pY705 →-0.371-2.459.003.02031
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GAPDH by RAET1L expression — UCEC

Box plot of GAPDH in RAET1L-low vs RAET1L-high samples in UCEC.

Explore this box plot interactively →

Exploration