RAET1L

Across TCGA pan-cancer cohorts, RAET1L RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RAET1L data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RAET1L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAET1L expression acts as an unfavorable survival marker, although some lineages such as ESCA and KICH show a favorable association.

KIRC, BRCA, and LUAD are the cancer types where RAET1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.619	0.854	.003	77	view →
BRCA	OS	Tertile	III,IV	0.827	0.966	<.001	75	view →
LUAD	OS	Tertile	All	0.234	0.430	<.001	56	view →
SKCM	OS	Quartile	All	0.659	0.799	<.001	32	view →
BLCA	DFS	Quartile	II,III,IV	0.262	0.439	.012	29	view →
ACC	DFS	Quartile	All	0.371	0.774	.008	28	view →
GBM	DFS	Tertile	All	0.173	0.428	<.001	27	view →
MESO	OS	Tertile	III,IV	0.253	0.523	.001	25	view →
LIHC	OS	Quartile	All	0.502	0.754	<.001	24	view →
PAAD	DFS	Quartile	All	0.232	0.568	.012	12	view →
SCLC	DFS	Quartile	IV	0.137	0.449	.025	9	view →
ESCA	DFS	Median	All	0.912	0.555	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RAET1L–KIRC (DFS)

Open the KIRC breakdown →