RAET1L

Across TCGA cell cohorts, RAET1L mutation is significantly associated with the mutation status of many other genes, with 1,200 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAET1L-associated genes across cancer lineages are HELB, DTL, and VAPA. Each is linked with RAET1L in more than 1 cancer types. Because this analysis shows association rather than direction, both RAET1L-to-partner and partner-to-RAET1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HELB grouped by RAET1L-low versus RAET1L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAET1L→partner) and Y-score (partner→RAET1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HELB →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	DTL →	+5.321	+5.894	.002	.002	1	2
LARGE_INTESTINE	VAPA →	+4.329	+4.329	.001	.001	1	2
LARGE_INTESTINE	LILRB5 →	+2.574	+4.182	.003	.003	1	2
LARGE_INTESTINE	WASL →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	EXPH5 →	+2.043	+3.693	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,200 associations by consensus.

HELB by RAET1L expression — BLOOD_Leukemia

Explore this box plot interactively →