RAET1E

Across TCGA patient cohorts, RAET1E mutation is significantly associated with the RNA expression of many other genes, with 358 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAET1E-associated genes across cancer lineages are MIR1179, C5orf66-AS2, and RPL23AP90. Each is linked with RAET1E in more than 1 cancer types. Because this analysis shows association rather than direction, both RAET1E-to-partner and partner-to-RAET1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1179 grouped by RAET1E-low versus RAET1E-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAET1E→partner) and Y-score (partner→RAET1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	2
SKCM	C5orf66-AS2 →	+0.018	+5.362	<.001	.005	3	1
UCEC	RPL23AP90 →	+0.358	+2.539	.003	.004	3	1
UCEC	STMN1P1 →	+0.456	+3.330	.002	.009	3	1
UCEC	CCL4L2 →	+1.121	+3.459	.001	.005	3	1
UCEC	TRBV12-4 →	+0.712	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

MIR1179 by RAET1E expression — COAD

Explore this box plot interactively →