RAET1E

Across TCGA pan-cancer cohorts, RAET1E RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RAET1E’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RAET1E RNA is repressed in tumor relative to normal tissue. In most cancer types RAET1E is over-expressed in tumor, although a few such as KIRP and HNSC show the opposite, repressed pattern.

KIRP, HNSC, and KIRC are the cancer types where RAET1E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAET1E RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−1.508	<.001	11	view →
HNSC	All	All	−1.367	<.001	10	view →
KIRC	Male	All	−0.862	<.001	10	view →
KICH	Female	All	−1.635	<.001	9	view →
THCA	Male	All	+1.205	<.001	9	view →
LUAD	All	II,III,IV	+0.649	<.001	7	view →
LIHC	Male	All	+0.173	<.001	7	view →
BRCA	All	All	+0.209	.029	4	view →
CHOL	All	II,III,IV	+0.520	.027	2	view →
UCEC	All	All	−0.506	<.001	2	view →
COAD	Female	III,IV	+0.377	.048	2	view →
PRAD	All	All	−0.213	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RAET1E–KIRP

Open the KIRP breakdown →