RAET1E

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAET1E mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAET1E-associated genes across cancer lineages are GATA6, Annexin-1, and TIGAR. Each is linked with RAET1E in more than 1 cancer types. Because this analysis shows association rather than direction, both RAET1E-to-partner and partner-to-RAET1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA6 grouped by RAET1E-low versus RAET1E-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAET1E→partner) and Y-score (partner→RAET1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGATA6 →-0.210-2.992.018.03631
UCECAnnexin-1 →+0.575+2.827.037.03531
UCECTIGAR →+0.203+2.196.011.03431
UCECCaspase-7-cleavedD198 →+0.705+2.827.023.03531
UCECTFRC →+0.573+3.321.039.01021
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GATA6 by RAET1E expression — UCEC

Box plot of GATA6 in RAET1E-low vs RAET1E-high samples in UCEC.

Explore this box plot interactively →

Exploration