RAD54L

Across TCGA cell cohorts, RAD54L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD54L-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Mitotic nuclear division, and Regulation of cell cycle G2/M phase transition. Each is linked with RAD54L in more than 19 cancer types. Because this analysis shows association rather than direction, both RAD54L-to-partner and partner-to-RAD54L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/M transition of mitotic cell cycle grouped by RAD54L-low versus RAD54L-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54L→partner) and Y-score (partner→RAD54L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of G2/M transition of mitotic cell cycle →	+0.085	+1.086	<.001	<.001	3	20
OVARY	Mitotic nuclear division →	+0.103	+0.898	<.001	<.001	3	20
BONE	Regulation of cell cycle G2/M phase transition →	+0.077	+1.206	.002	.007	3	20
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.202	+1.640	<.001	<.001	3	20
OVARY	Nuclear division →	+0.089	+0.926	<.001	<.001	3	20
BONE	DNA integrity checkpoint signaling →	+0.117	+1.510	.001	.007	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,108 associations by consensus.

Regulation of G2/M transition of mitotic cell cycle by RAD54L expression — BREAST

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