Across TCGA patient cohorts, RAD54B mutation is significantly associated with the RNA expression of many other genes, with 5,190 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD54B-associated genes across cancer lineages are RNU6-42P, NFYBP1, and KRTAP12-6P. Each is linked with RAD54B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAD54B-to-partner and partner-to-RAD54B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54B→partner) and Y-score (partner→RAD54B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-42P →	+0.429	+1.571	.003	.004	3	3
UCEC	NFYBP1 →	+0.143	+1.442	<.001	.006	3	3
BRCA	KRTAP12-6P →	+0.068	+4.201	<.001	.007	3	2
UCEC	ZNF852 →	+0.347	+2.606	<.001	<.001	3	2
UCEC	TCAIM →	+0.358	+3.906	.001	<.001	3	2
UCEC	CLK3 →	+0.183	+3.376	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,190 associations by consensus.

Exploration

RAD54B survival (RNA) · tumor vs normal (RNA) · all RAD54B data types