Across TCGA cell cohorts, RAD54B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RAD54B-associated genes across cancer lineages are AVP, OR52E5, and TEX28. Each is linked with RAD54B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD54B-to-partner and partner-to-RAD54B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54B→partner) and Y-score (partner→RAD54B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	AVP →	+0.060	+4.108	<.001	.005	3	2
LUNG_NSCLC_LUSC	OR52E5 →	+0.017	+4.108	<.001	.005	3	1
LUNG_NSCLC_LUAD	TEX28 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	C1orf232 →	+0.030	+4.887	.002	.009	3	1
LARGE_INTESTINE	REG1B →	+3.348	+3.196	<.001	.007	3	1
SKIN	EDDM3B →	+0.034	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

RAD54B survival (RNA) · tumor vs normal (RNA) · all RAD54B data types