RAD52

Across TCGA cell cohorts, RAD52 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,139 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RAD52-associated GO terms across cancer lineages are Constitutive heterochromatin formation, Regulation of nucleotide-excision repair, and Telomere organization. Each is linked with RAD52 in more than 16 cancer types. Because this analysis shows association rather than direction, both RAD52-to-partner and partner-to-RAD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Constitutive heterochromatin formation grouped by RAD52-low versus RAD52-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD52→partner) and Y-score (partner→RAD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Constitutive heterochromatin formation →	+0.094	+0.692	<.001	<.001	3	17
BONE	Regulation of nucleotide-excision repair →	+0.114	+1.094	.003	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Telomere organization →	+0.090	+1.246	<.001	.002	3	16
BONE	Regulation of telomere maintenance →	+0.104	+1.247	<.001	<.001	3	16
BONE	Recombinational repair →	+0.125	+1.114	<.001	<.001	3	16
BONE	DNA double-strand break processing involved in repair via single-strand annealing →	+0.088	+1.013	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,139 associations by consensus.

Constitutive heterochromatin formation by RAD52 expression — OVARY

Explore this box plot interactively →