RAD52

Across TCGA cell cohorts, RAD52 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RAD52-associated genes across cancer lineages are H1-1, HSFY1, and SLC15A5. Each is linked with RAD52 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD52-to-partner and partner-to-RAD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H1-1 grouped by RAD52-low versus RAD52-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD52→partner) and Y-score (partner→RAD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	H1-1 →	+0.099	+4.054	<.001	.004	3	1
SKIN	HSFY1 →	+0.013	+6.022	<.001	.001	3	1
SKIN	SLC15A5 →	+0.063	+4.977	<.001	.007	3	1
SKIN	CLRN2 →	+0.025	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

H1-1 by RAD52 expression — LARGE_INTESTINE

Explore this box plot interactively →